Is Tretinoin Anti-Aging: Using This Retinoid for Wrinkles

If you click a link on this page and make a purchase, we may receive a small commission at no extra cost to you. Learn more.

In the realm of anti-aging skincare, there are numerous products and ingredients to consider. Retinoids, in particular, have gained popularity over the past several years for their ability to rejuvenate the skin and fight signs of aging.

Tretinoin is one prescription-strength retinoid that’s widely used to treat imperfections. But, does this cream work for wrinkles? Continue reading to find out.

How To Use Tretinoin as an Anti-Aging Gel or Cream

Tretinoin Retin A

If you’re interested in using tretinoin for wrinkles, you’ll first need to visit a dermatologist. Tretinoin (or Retin-A, which is its brand name) is only available with a prescription – you can’t get it over-the-counter.

After receiving a prescription for tretinoin and picking it up at the pharmacy, you can start using it in your skincare routine. But, know that all retinoids, including over-the-counter retinol, take some time to get used to. Your skin needs time to adjust to these potent formulas.

beautiful lady and mirror

For tretinoin, the skin may need 2 to 6 weeks to adjust. During this period, you may experience dryness, peeling, and general skin irritation. These effects are normal and will go away over time. [1]

To limit irritation during this adjustment period, start off by using just a small, pea-sized amount of cream on the face every other night (or as recommended by your dermatologist). Additionally, apply a moisturizer before your tretinoin, giving it a full 15 minutes to absorb before laying on the retinoid cream.

Serious side effects of tretinoin that you should contact your doctor about include blistering, crusting, severe burning, severe swelling, and skin discoloration. [2]

Most people start to notice an improvement in their skin 2 to 6 weeks after starting to use tretinoin cream or gel. This product works by increasing the skin cell cycle, which allows new, healthy skin cells to replace the old, damaged cells. It also increases collagen production for stronger, firmer skin. [3]


Is tretinoin good for anti-aging?

Yes, tretinoin can effectively reduce signs of aging including wrinkles, dark spots, and sun damage.

What percentage of tretinoin is anti-aging?

For anti-aging, 0.05% tretinoin is widely recommended. [4]

When should I start using tretinoin anti-aging?

You can start using tretinoin in your 20s to prevent signs of aging. [5]

Does tretinoin prevent wrinkles?

Yes, tretinoin helps prevent wrinkles by stimulating collagen production and increasing skin cell turnover.

Does tretinoin cause wrinkles under eyes?

No. Tretinoin won’t cause wrinkles under the eyes, but it can dry out this delicate area. So, dermatologists often recommend not applying tretinoin directly to the under-eye area. [6]

Will tretinoin help with wrinkles?

Yes, tretinoin helps reduce the appearance of wrinkles and fine lines.

What are the before and after results of tretinoin for face?

With consistent use, the before and after results of tretinoin reveal a noticeable improvement in wrinkles, uneven skin tone, and rough skin. [6]

What do Retin A week-by-week pictures reveal?

Week–by-week Retin A pictures show that it smooths, evens out, and brightens the skin after a few months of consistent use.

What strength of tretinoin cream is best for wrinkles?

0.05% tretinoin cream is generally recommended for wrinkles and other signs of aging.

What’s the correct tretinoin dosage?

The tretinoin dosage that’s most often recommended for aging is 0.05%.

How long does it take for Retin A to work on wrinkles?

It can take 6 months or longer to notice an improvement from Retin A. The results of this retinol treatment will continue to improve over time.

Conclusion: The Benefits of Tretinoin for Fine Lines, Acne, and Under-Eye Bags 

happy lady

Tretinoin has been widely proven as an effective treatment for fine lines, acne, under-eye bags, and other skin imperfections. While it does require a prescription, it can make a noticeable improvement in your skin and help you beat the skin aging process.

Ready to start rejuvenating your skin? Take a look at our review of leading anti-aging creams to find the best products for your beauty routine.



Avatar for Megan Foley

Megan has been a freelance writer and editor since 2016. In that time, she’s penned a diverse collection of articles for online publication, with a focus on skincare and beauty. From in-depth product reviews to concise marketing content, Megan is passionate about developing content that informs, entertains, and inspires.