LifeCell Overnight Hand Treatment Review 2022: Is it a Good Hand Cream?

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It doesn’t matter how many anti-aging serums and creams you heap onto your face – neglect to give your hands the same TLC and they’ll instantly give away your true age, no matter how youthful your face may look.

There’s a reason for this; not only are there fewer oil glands on the hands, meaning that the skin here dries and wrinkles much faster, but our hands are also frequently exposed to the sun, not to mention all of the wear and tear they experience each day.

The pandemic hasn’t helped either – all of that hand washing and sanitizing may protect you from viruses, but it leaves the skin parched, which, again, exacerbates skin aging.

The solution? A quality hand cream, which is where the LifeCell Overnight Hand Treatment comes in. We were skeptical at first – we’ve seen so many hand creams in the past that are nothing more than clever marketing gimmicks.

They’re filled with not-so-nice ingredients that may temporarily soften the skin but don’t do much for it in the long run. Is LifeCell’s Overnight Hand Treatment any different? Read on to find out…

How each product is reviewed

Each and every product mentioned on our site has been tested by one of the team members of Pierre Michel Beauty. We do not receive any sponsorship from the brands and all comments are our own. From time to time, we also refer to online reviews and include information about how other people use the products.

Hot Take: I tried the LifeCell Overnight Hand Treatment and found that it is like a really good moisturizer that has the added bonus of removing age spots. Read on as I share my detailed findings.

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What is the LifeCell Overnight Hand Treatment?

Produced by South Beach Skincare Inc., the LifeCell Overnight Hand Treatment is a lightweight hand cream designed to turn back the clock when it comes to the skin on the hands.

According to South Beach Skincare, those who use the product regularly will start to notice a difference in just a few weeks.


How Does This Advanced Skin Product Work and How to Use It?

This all-in-one treatment works in a few ways. Firstly, it deeply hydrates the skin. As mentioned, with fewer oil glands in this area, extra hydration is desperately needed to keep skin cells functioning optimally.

In addition to being a hydrating hand treatment, this formula also targets discoloration. This is a common issue with the skin on the hands due to all of the unprotected UV exposure it receives. As a result, dark spots appear with age, something that this treatment will help to tackle.

Using the hand cream is easy. South Beach Skincare recommends using it in the evenings by applying a small amount of the product to the back of your hands. Then, rub it gently into your hands until it has been fully absorbed.

Key Ingredients of LifeCell Overnight Hand Treatment

lifecell overnight hand treatment reviews

You should always take a close look at the ingredient list of any product you’re considering using, even if you’re already a fan of the brand. In the case of this hand treatment, we were impressed with the ingredients that we saw, with some of our favorites being:

Ingredient nameKey benefits
Vitamin CA must-have in every anti-aging product for its smoothing and brightening effects, this hand cream contains three forms of vitamin C; vitamin C palmitate, magnesium ascorbyl phosphate, and ascorbic acid
Vitamin E acetateProtects the skin from environmental damage while also offering up powerful antioxidant activity (1)
Sodium hyaluronateThe salt form of hyaluronic acid, sodium hyaluronate deeply hydrates the skin, leaving it looking plump and radiant
Bearberry leaf extractA natural brightening ingredient that will leave you with a more even skin tone
Licorice root extractBrightens skin tone, reduces the appearance of dark spots, and delivers potent antioxidants. Licorice root extract is a common ingredient in skin-brightening products
Veronica officinalis extractA traditional healing plant that reduces wrinkles and sagging skin
Alchemilla vulgaris extractContains powerful antioxidants that fight free radicals, preventing and repairing skin cell damage
Lemon balm leaf extractanother ingredient that reduces oxidative stress in the skin, therefore delaying the skin aging process (2)
Shea butterNot only is it a powerful anti-inflammatory, but shea butter also helps to repair and strengthen the skin barrier
Organic argan oilRegular use has been proven to prevent skin aging and help to maintain a youthful appearance (3)
Olive fruit oilPacked with a huge selection of skin-loving vitamins and antioxidants
Silicon oxideBoosts collagen synthesis, the protein responsible for keeping the skin smooth and taut (4)
Iron oxide and titanium dioxideTogether, iron oxide and titanium dioxide help to provide important UV protection to the skin


What Are the Benefits of The LifeCell Overnight Hand Treatment Cream?

lifecell overnight hand treatment

Includes Natural Extracts

As you can see from the ingredients we’ve discussed, there are numerous natural extracts in this hand cream. These are often favored over chemical alternatives since they offer a greater range of benefits with fewer side effects.

Contains Three Forms of Vitamin C

As mentioned, there are three forms of vitamin C in this product. The most powerful is ascorbic acid, but this is also known for being relatively unstable. South Beach Skincare has taken this into account and added in two highly stabilized vitamin C forms; magnesium ascorbyl phosphate and vitamin C palmitate.

Treats Discoloration and Reduces the Appearance of Age Spots

This formula contains a number of ingredients that, on their own, are capable of fading age spots. Combine them together and you’ll be able to reduce those dark spots, giving your hands a more even and balanced finish.

Hydrates and Evens the Skin Tone

Not only does discoloration result in an uneven skin tone, but so does a lack of hydration. By infusing your skin cells with extra moisture, you’ll enjoy an all-around glow that culminates in a more youthful appearance overnight.

Customer Reviews and Ratings

So, what do other people think of this hand treatment? Turns out, the majority absolutely love it. We’ve scoured through hundreds of product reviews and have struggled to find anything negative.

Those who have been trying to reduce the signs of aging on their hands have been delighted with how bright, smooth, and soft their hands are after using this product, making it hardly surprising that just about everyone rates it 5/5.

lifecell overnight hand treatment cream customer reviews

Purchase and Shipping Information

Wondering how to get your hands on this treatment, as well as other LifeCell products? Here’s what you need to know:

Where to Buy the LifeCell Overnight Hand Treatment Cream?

There are numerous retailers that sell this treatment, but we would highly recommend purchasing it from LifeCell’s official website. This way, you won’t end up with a fake, and you’ll also be able to enjoy the frequent discounts offered by the brand.

Plus, you will also enjoy free shipping and a 30-day money-back guarantee. If you are not satisfied with your purchase, you can get a refund for it. That’s pretty much risk-free shopping!



LifeCell offers a few different shipping options. To save money, you can opt for free shipping, which takes a few days. Alternatively, go for overnight express if your hands are in desperate need of some attention.

LifeCell Overnight Hand Treatment Review Conclusion

Nobody wants their hands to be covered in age spots and wrinkles, which is why we always recommend adding a good hand cream into your skincare routine as early on in life as possible.

While prevention may be better than cure, LifeCell’s Overnight Hand Treatment shows that it’s never too late to start paying attention to the skin on your hands. Even though you may have neglected them in your earlier years, this cream will restore that youthful glow and bounce that your hands have been lacking.

Get your own on LifeCell’s official website and enjoy authenticity, free shipping, and a 30-day money-back guarantee now!

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  1. Keen, Mohammad Abid, and Iffat Hassan. “Vitamin E in dermatology.” Indian dermatology online journal vol. 7,4 (2016): 311-5. doi:10.4103/2229-5178.185494 (]
  2. Ramanauskienė, Kristina et al. “Assessment of Lemon Balm (Melissa officinalis L.) Hydrogels: Quality and Bioactivity in Skin Cells.” Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 635975. doi:10.1155/2015/635975 (]
  3. Lizard, Gérard et al. “Benefits of Argan Oil on Human Health-May 4-6 2017, Errachidia, Morocco.” International journal of molecular sciences vol. 18,7 1383. 28 Jun. 2017, doi:10.3390/ijms18071383 (]
  4. Araújo, Lidiane Advincula de et al. “Use of silicon for skin and hair care: an approach of chemical forms available and efficacy.” Anais brasileiros de dermatologia vol. 91,3 (2016): 331-5. doi:10.1590/abd1806-4841.20163986 (]
Avatar for Megan Foley

Megan has been a freelance writer and editor since 2016. In that time, she’s penned a diverse collection of articles for online publication, with a focus on skincare and beauty. From in-depth product reviews to concise marketing content, Megan is passionate about developing content that informs, entertains, and inspires.