The Best Anti-Aging Hand Cream: Our Top Picks

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From washing your hands to doing the dishes and even simply spending time in the sun, your hands are subject to skin aging. Just like the skin on your face, the skin on your hands can wrinkle, crease, and lose elasticity over time.

But, while we tediously devise skincare regimens to keep our faces young, our hands tend to be treated like the forgotten middle child. That’s why we’re here with a lineup of the best anti-aging hand creams. It’s time to fill the gap in your beauty routine and maintain your hands’ youthful glow!

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What Is the Best Hand Cream for Aging Hands?

When it comes to hand creams for wrinkled, aging hands, there’s a variety of products on the market. We’ve sifted through the available options and determined the top ten.

These stellar hand creams are formulated with potent ingredients to counteract visible signs of aging on the hands.

The Best Overall Anti-Aging Cream for Wrinkle-Free Hands

lifecell overnight hand treatment

LifeCell Overnight Hand Treatment

The Overnight Hand Treatment from LifeCell is designed to combat skin aging as you sleep. It contains potent ingredients including retinol, vitamin C, vitamin E, bearberry extract, ceramides, and natural plant oils.

LifeCell’s Overnight Hand Treatment is effective for reducing the appearance of age spots, dark spots, and discoloration. It can help you achieve a more even skin tone on the hands. Additionally, this cream provides all-day hydration, ensuring that the hands are soft to the touch.


  • Contains ingredients, including retinol, that are proven to fight skin aging [1]
  • Effective for age spots, dark spots, and discoloration with lightening ingredients including bearberry extract [2]
  • Lightweight, fast-absorbing formula
  • Provides results within only a few weeks


  • More expensive than other options on this list
  • Increases sun sensitivity


The Best Age-Defying Hand and Nail Cream

Caudalie Hand and Nail Repairing Cream

Caudalie Hand and Nail Repairing Cream

The Caudalie Hand and Nail Repairing Cream is designed to nourish the hands while protecting them against dryness and outside stressors. This hand cream also bolsters the nails and cuticles for more beautiful and resilient hands.

This hand and nail cream is among the best anti-aging hand creams because its formula contains 98% natural-origin (and effective) ingredients, including:

  • Shea butter, which is packed with vitamins E, A, D, and F
  • Polyphenols, which deliver a powerful dose of antioxidants to the skin
  • Grapeseed oil, which provides deep hydration and contains omega 6 to ease inflammation [3]


  • Safe for all skin types, including normal, dry, oily, combination, and sensitive skin
  • Vegan, natural formula
  • Non-greasy formula
  • Strengthens the skin and nails to prevent future damage
  • Protects against chemical and environmental aggressors that can dry out the hands


  • The scent may be too strong for some users


The Top-Rated Hand Cream for Wrinkles and Dryness

Neutrogena Norwegian Formula Hand Cream

Neutrogena Norwegian Formula Hand Cream

The Neutrogena Norwegian Formula Hand Cream is one of the most highly rated anti-aging hand creams around. It’s formulated to soothe chapped, cracked skin after a single application.

The main ingredient in this hand cream is glycerin. Glycerin is a natural compound that’s been scientifically proven to treat dry skin [4]. Along with helping to keep the hands smooth and soft, the Norwegian Formula Hand Cream has been accepted by the National Eczema Association.


  • Dermatologist-recommended brand
  • Scientifically proven to heal dry, cracked skin
  • Thousands of 5-star customer reviews


  • Not all users enjoy this cream’s light scent.


The Best Hand Cream Formula with Hyaluronic Acid

Cerave healing ointment

CeraVe Healing Ointment

The CeraVe Healing Ointment is formulated with hyaluronic acid, ceramides, and petrolatum to heal extremely dry skin. It creates a protective layer over the skin to improve the skin barrier’s function for up to 8 hours.

  • Hyaluronic acid has humectant properties, meaning that it helps the skin retain moisture.
  • Ceramides work to rebuild and protect the skin barrier.
  • Petrolatum (petroleum jelly) forms a protective barrier around the skin, which prevents moisture loss [5].

This healing ointment from CeraVe is considered a skin protectant, rather than a traditional lotion. This makes it a popular balm for irritated, chapped, and flaky skin, as well as inflammatory skin conditions.


  • Safe for all skin types
  • Free of dyes, fragrance, and lanolin to prevent irritation
  • Non-comedogenic (won’t clog pores)
  • Protects the skin barrier for up to 8 hours
  • Effective for eczema and other inflammatory skin conditions


  • The formula is very thick and doesn’t absorb quickly
  • Some users find that this ointment has a greasy, oily feel.


The Best Fast-Absorbing Hand Cream for Aging Skin

Nécessaire – The Hand Cream

Nécessaire - The Hand Cream

The Hand Cream from Nécessaire is designed to moisturize, nourish, and protect the skin. It’s a peptide and multi-vitamin cream that you can use as a daily moisturizer to help make the hands silky smooth.

Nécessaire’s hand cream formula provides a generous dose of the following ingredients:

  • Peptides

Peptides are amino acids that can help boost collagen production and natural elastin production [6]. As a result, this peptide-rich hand cream formula improves skin elasticity.

  • Niacinamide

Niacinamide, a type of vitamin B-3, helps the skin produce new skin cells. It also offers protection against environmental aggressors, such as pollution [7].

  • Vitamin C

Vitamin C fights the signs of aging skin, including wrinkles and dark spots. It’s effective for not only your face – but vitamin C can also effectively rejuvenate your hands [8].

  • Vitamin E

Vitamin E supports the skin barrier and protects skin cells against free radical damage [9].

  • Omega-6 and Omega-9

As types of fatty acids, omega-6 and omega-9 both help retain skin hydration.


  • Lightweight, fast-absorbing formula
  • Vegan and cruelty-fee
  • Non-comedogenic
  • Climate neutral-certified brand
  • Fragrance-free and hypoallergenic
  • Safe for sensitive skin and users with eczema


  • Doesn’t provide long-lasting hydration


The Best Hand Cream To Block UV Rays and Prevent Aging

Supergoop Handscreen SPF 40

Supergoop! Handscreen SPF 40

Sun exposure is a key cause of premature skin aging on the face, hands, and any other area that sees the sun. Harmful UV rays from the sun break down the fibers that keep the skin elastic. This can lead to wrinkles, dryness, and age spots.

Applying sunscreen to your hands can help you maintain a smooth, youthful glow. Supergoop! Handscreen SPF 40 was designed for this exact purpose.

This unique product is the first preventative hand cream for signs of aging. It provides broad-spectrum SPF 40 with avobenzone, octisalate, and octocrylene.

For deep hydration, the formula also contains a variety of antioxidants and natural oils, including orange peel oil, clove leaf oil, and radish seed oil.


  • Protects against signs of aging caused by excess sun exposure
  • Vegan and cruelty-free
  • Hydrating formula with antioxidants and plant oils
  • Free of oxybenzone, PABA, anatase titanium dioxide, and octinoxate
  • Available in two sizes: 6.7 fluid oz. and 1 fluid oz.


  • Doesn’t treat existing signs of aging


The Best Hand Plumping Cream for Veins and Crepey Skin

Beauty Pie Super Retinol Anti-Aging Hand Cream

Beauty Pie Super Retinol Anti-Aging Hand Cream

The Beauty Pie Super Retinol Anti-Aging Hand Cream was formulated in Switzerland with a range of powerful ingredients. It can be used to treat sun spots, lost elasticity, and crepey skin on the hands.

The Super Retinol Anti-Aging cream contains a one-of-a-kind blend of micro-encapsulated retinol, biotech pseudo-collagen, shea butter, and bio-sugar moisture magnets.

  • Micro-Encapsulated Retinol

Retinol increases collagen production to improve the appearance of wrinkles and fine lines. It also increases skin cell turnover to remove dead skin cells and even out the skin tone.

  • Biotech Pseudo-Collagen

This ingredient has a remarkable moisture-binding capacity. It smooths, plumps, and softens the skin.

  • Shea butter

Shea butter is a popular, natural ingredient in anti-aging products. It softens and soothes dry skin.

  • Bio-Sugar Moisture Magnets

Bio-sugar moisture magnets are found at a 5% concentration in this anti-aging cream. It’s intended to provide deep, long-term moisture to the skin.


  • Contains retinol to noticeably fight skin aging, including wrinkles, thinning skin, and discoloration
  • Unique ingredients including biotech pseudo-collagen and bio-sugar moisture magnets plump and moisturize the skin
  • Fragrance-free
  • Vegan and cruelty-free


  • Not suitable for sensitive skin
  • More expensive than other options on this list
  • Increases sun sensitivity


The Best Hand Cream for Younger-Looking Hands

Skincare LdeL Cosmetics Retinol Anti-Aging Hand Cream

Skincare LdeL Cosmetics Retinol Anti-Aging Hand Cream

The Skincare LdeL Cosmetics Retinol Anti-Aging Hand Cream is a popular product to rejuvenate the hands. Its prime ingredient is retinol, which helps boost collagen production and exfoliate the skin for smoother, more beautiful hands.

Along with retinol, this cream from Skincare LdeL Cosmetics contains green tea, vitamin E, and vitamin C. These anti-wrinkle ingredients further soften fine lines. Additionally, this cream deeply conditions and protects the nails and cuticles for healthy, elegant hands.

Skincare LdeL Cosmetics has been in business since 1987 and has sold over 10 million units. These facts speak to the brand’s skincare expertise.


  • Visibly reduces the appearance of wrinkles and fine lines with consistent use
  • Brightens the skin and treats age spots
  • More affordable than other retinol hand creams
  • Non-greasy formula


  • Not all users enjoy this cream’s scent.
  • May take up to 45 days to see results
  • Increases sun sensitivity


The Best Hand Lotion for Eczema

Skinfix Hand Repair Cream

Skinfix Hand Repair Cream

The Skinfix Hand Repair Cream has been clinically shown to treat dry, cracked skin on the hands. It can even be used to treat and prevent eczema flares.

Along with deeply hydrating the skin, this product can be used as an anti-aging hand product. It can address fine lines, wrinkles, and redness.

Colloidal oatmeal, allantoin, and sweet almond oil are the key ingredients in the Skinfix Hand Repair Cream.

  • Colloidal oatmeal acts as a natural protective ingredient to ease itchiness and irritation.
  • Allantoin is a naturally-derived humectant that increases cell turnover, boosts hydration, and helps heal the skin.
  • Sweet almond oil is packed with nutrients and nourishes irritated skin.


  • Vegan, gluten-free, and cruelty-free
  • Safe for normal, dry, combination, oily, and sensitive skin
  • Fast-absorbing formula


  • Some users find that this cream has an oily finish.


The Best Non-Greasy Anti-Aging Hand Cream

Mario Badescu Special Hand Cream With Vitamin E

Mario Badescu Special Hand Cream With Vitamin E

This antioxidant-rich hand cream is lightweight with a smooth finish. It’s designed to leave the hands with a soft and silky feel.

Some of the ingredients in the Mario Badescu Special Hand Cream include:

  • Glyceryl stearate, which is an emollient
  • Paraffinum liquidum (which contains mineral oil and huile mineral) is made from petroleum and acts as an emollient and skin protectant.
  • Corn oil, which is used as an occlusive, meaning that it helps lock in moisture
  • Tocopheryl acetate, which is made from vitamin E and used as an antioxidant and emollient
  • Retinyl palmitate, which is an ester of retinol and palmitic acid and acts as an emollient
  • Wheat germ oil, which helps keep moisture in the skin


  • Comes in a jar or a travel-friendly tube
  • Gluten-free and cruelty-free
  • Ideal for all skin types


  • Not all users enjoy this floral cream’s scent.
  • May take time to fully absorb


Ingredients to Look for in an Anti-Wrinkle Hand Cream


Retinol is a form of vitamin A that’s widely used for skin concerns including signs of aging and acne. As we’ve mentioned earlier in this article, it works by stimulating the production of collagen and elastin, as well as speeding up the skin cell cycle.

Note that retinol can be irritating to sensitive skin. But, the skin can become accustomed to this ingredient over time. We recommend starting with a small amount and increasing the dosage as your skin adjusts.

Additionally, retinol increases the skin’s sensitivity to the sun. When you’re using a retinol product, make sure to diligently apply sunscreen every day (even if it’s cloudy!).

Vitamins E and C

Vitamins E and C both act as antioxidants and prevent oxidative stress in the body. In hand creams, these vitamins can brighten and help repair damaged skin.

Shea Butter

Shea butter is a fat derived from shea tree nuts. In skincare products, shea butter acts as an emollient, meaning that it forms a barrier to hold moisture in the skin.


Sunscreen can be used to protect against skin aging on the hands, rather than treat existing signs of aging. Used daily, sunscreen can prevent UV-ray damage and help keep the skin smooth.


Young woman massaging her hands with hand cream

Q: How do I restore wrinkles on my hands?

To restore wrinkles on the hands, it’s important to keep them hydrated by using a nourishing cream in your daily skincare routine. Improving the skin’s elasticity with retinol can also help smooth wrinkles on the hands.

Q: Does retinol help aging hands?

Retinol has been clinically proven to improve the appearance of aged skin [10]. It can improve the appearance of aging hands and help with concerns including fine lines, wrinkles, age spots, and lost elasticity.

Q: How can I make my hands look younger?

To make your hands look younger, first, make sure that you’re protecting them against the sun’s harsh UV rays with sunscreen. Then, keep the hands hydrated with creams containing natural ingredients. Additionally, exfoliate the hands (with retinol, for example) to remove dead skin cells and brighten the skin.

Q: What is the best treatment for aging hands?

If you’re seeking cosmetic treatments for aging hands, there are several options available to you. Laser therapy, chemical peels, and microdermabrasion are all rejuvenating treatments that can be performed at your dermatologist’s office [11]. For an at-home solution to aging hands, consider brightening hand lotions and creams.

Q: How do you get rid of old-looking hands?

To get rid of old-looking hands, it’s essential to care for your skin. Apply sunscreen every day before heading outside and slather on a moisturizing hand cream throughout the day. You can also consider topical overnight hand treatments for significant results.

Q: Can you tighten loose skin on hands?

With powerful ingredients like retinol, it’s possible to tighten loose skin on the hands.

Q: What home remedy can I use to make my hands look younger?

Various creams containing retinol are available over the counter and can give your hands a youthful glow.

Q: How can I make my 70-year-old hands look younger?

Deeply nourishing and moisturizing hand creams can make 70-year-old hands appear younger. By hydrating and trapping moisture in the skin, hand creams can help with dry, cracked, and flaking skin.

Conclusion: Choosing the Best Anti-Aging Hand Cream for Your Needs

If you’re seeking a hand cream that will leave your hands soft, smooth, and rejuvenated, there are countless products for you to choose from. Above, we listed our top ten anti-aging hand creams, each of which brings unique benefits to the table.

We can’t deny that the LifeCell Overnight Hand Treatment is our favorite for a dramatic improvement to aging hands. But, everyone’s skincare needs are a little different. For extreme skin dryness or irritation on the hands, don’t hesitate to talk to your dermatologist for professional advice.

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Avatar for Megan Foley

Megan has been a freelance writer and editor since 2016. In that time, she’s penned a diverse collection of articles for online publication, with a focus on skincare and beauty. From in-depth product reviews to concise marketing content, Megan is passionate about developing content that informs, entertains, and inspires.